Civets are equally susceptible to experimental infection by two different severe acute respiratory syndrome coronavirus isolates
Identifieur interne : 004E58 ( Main/Exploration ); précédent : 004E57; suivant : 004E59Civets are equally susceptible to experimental infection by two different severe acute respiratory syndrome coronavirus isolates
Auteurs : DONGLAI WU [République populaire de Chine] ; CHANGCHUN TU [République populaire de Chine] ; CHAOAN XIN [République populaire de Chine] ; HUA XUAN [République populaire de Chine] ; QINGWEN MENG [République populaire de Chine] ; YONGGANG LIU [République populaire de Chine] ; YEDONG YU [République populaire de Chine] ; YUNTAO GUAN [République populaire de Chine] ; YU JIANG [République populaire de Chine] ; XUNNAN YIN [République populaire de Chine] ; Gary Crameri [Australie] ; MUPING WANG [République populaire de Chine] ; CHANGWEN LI [République populaire de Chine] ; SHENGWANG LIU [République populaire de Chine] ; MING LIAO [République populaire de Chine] ; LI FENG [République populaire de Chine] ; HUA XIANG [République populaire de Chine] ; JINFU SUN [République populaire de Chine] ; JINDING CHEN [République populaire de Chine] ; YANWEI SUN [République populaire de Chine] ; SHOULIN GU [République populaire de Chine] ; NIHONG LIU [République populaire de Chine] ; DEXIA FU [République populaire de Chine] ; Bryan T. Eaton [Australie] ; Lin-Fa Wang [Australie] ; XIANGANG KONG [République populaire de Chine]Source :
- Journal of virology [ 0022-538X ] ; 2005.
Descripteurs français
- Pascal (Inist)
English descriptors
Abstract
Severe acute respiratory syndrome (SARS) was caused by a novel virus now known as SARS coronavirus (SARS-CoV). The discovery of SARS-CoV-like viruses in masked palm civets (Paguma larvata) raises the possibility that civets play a role in SARS-CoV transmission. To test the susceptibility of civets to experimental infection by different SARS-CoV isolates, 10 civets were inoculated with two human isolates of SARS-CoV, BJ01 (with a 29-nucleotide deletion) and GZ01 (without the 29-nucleotide deletion). All inoculated animals displayed clinical symptoms, such as fever, lethargy, and loss of aggressiveness, and the infection was confirmed by virus isolation, detection of viral genomic RNA, and serum-neutralizing antibodies. Our data show that civets were equally susceptible to SARS-CoV isolates GZ01 and BJ01.
Affiliations:
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Civets are equally susceptible to experimental infection by two different severe acute respiratory syndrome coronavirus isolates</title><author><name sortKey="Donglai Wu" sort="Donglai Wu" uniqKey="Donglai Wu" last="Donglai Wu">DONGLAI WU</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences</s1><s2>Harbin</s2><s3>CHN</s3><sZ>1 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ><sZ>10 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>16 aut.</sZ><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>26 aut.</sZ></inist:fA14><country>République populaire de Chine</country><wicri:noRegion>Harbin</wicri:noRegion></affiliation></author><author><name sortKey="Changchun Tu" sort="Changchun Tu" uniqKey="Changchun Tu" last="Changchun Tu">CHANGCHUN TU</name><affiliation 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uniqKey="Hua Xuan" last="Hua Xuan">HUA XUAN</name><affiliation wicri:level="3"><inist:fA14 i1="04"><s1>Department of Military Veterinary, Changchun University of Agriculture and Animal Sciences</s1><s2>Changchun</s2><s3>CHN</s3><sZ>4 aut.</sZ></inist:fA14><country>République populaire de Chine</country><placeName><settlement type="city">Changchun</settlement><region type="province">Jilin</region><region type="groupement">Dongbei</region></placeName></affiliation></author><author><name sortKey="Qingwen Meng" sort="Qingwen Meng" uniqKey="Qingwen Meng" last="Qingwen Meng">QINGWEN MENG</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences</s1><s2>Harbin</s2><s3>CHN</s3><sZ>1 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ><sZ>10 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>16 aut.</sZ><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>26 aut.</sZ></inist:fA14><country>République populaire de Chine</country><wicri:noRegion>Harbin</wicri:noRegion></affiliation></author><author><name sortKey="Yonggang Liu" sort="Yonggang Liu" uniqKey="Yonggang Liu" last="Yonggang Liu">YONGGANG LIU</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences</s1><s2>Harbin</s2><s3>CHN</s3><sZ>1 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ><sZ>10 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>16 aut.</sZ><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>26 aut.</sZ></inist:fA14><country>République populaire de Chine</country><wicri:noRegion>Harbin</wicri:noRegion></affiliation></author><author><name sortKey="Yedong Yu" sort="Yedong Yu" uniqKey="Yedong Yu" last="Yedong Yu">YEDONG YU</name><affiliation wicri:level="3"><inist:fA14 i1="05"><s1>Guangdong Provincial Veterinary Station of Epidemic Prevention and Supervision</s1><s2>Guangzhou</s2><s3>CHN</s3><sZ>7 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>République populaire de Chine</country><placeName><settlement type="city">Jiangmen</settlement><region type="province">Guangdong</region></placeName></affiliation></author><author><name sortKey="Yuntao Guan" sort="Yuntao Guan" uniqKey="Yuntao Guan" last="Yuntao Guan">YUNTAO GUAN</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences</s1><s2>Harbin</s2><s3>CHN</s3><sZ>1 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ><sZ>10 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>16 aut.</sZ><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>26 aut.</sZ></inist:fA14><country>République populaire de Chine</country><wicri:noRegion>Harbin</wicri:noRegion></affiliation></author><author><name sortKey="Yu Jiang" sort="Yu Jiang" uniqKey="Yu Jiang" last="Yu Jiang">YU JIANG</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Military Veterinary Research Institute, Academy of Military Medical Sciences</s1><s2>Changchun</s2><s3>CHN</s3><sZ>2 aut.</sZ><sZ>9 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ></inist:fA14><country>République populaire de Chine</country><placeName><settlement type="city">Changchun</settlement><region type="province">Jilin</region><region type="groupement">Dongbei</region></placeName></affiliation></author><author><name sortKey="Xunnan Yin" sort="Xunnan Yin" uniqKey="Xunnan Yin" last="Xunnan Yin">XUNNAN YIN</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences</s1><s2>Harbin</s2><s3>CHN</s3><sZ>1 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ><sZ>10 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>16 aut.</sZ><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>26 aut.</sZ></inist:fA14><country>République populaire de Chine</country><wicri:noRegion>Harbin</wicri:noRegion></affiliation></author><author><name sortKey="Crameri, Gary" sort="Crameri, Gary" uniqKey="Crameri G" first="Gary" last="Crameri">Gary Crameri</name><affiliation wicri:level="1"><inist:fA14 i1="06"><s1>Commonwealth Scientific and Industrial Research Organization Livestock Industries, Australian Animal Health Laboratory</s1><s2>Geelong</s2><s3>AUS</s3><sZ>11 aut.</sZ><sZ>24 aut.</sZ><sZ>25 aut.</sZ></inist:fA14><country>Australie</country><wicri:noRegion>Geelong</wicri:noRegion></affiliation></author><author><name sortKey="Muping Wang" sort="Muping Wang" uniqKey="Muping Wang" last="Muping Wang">MUPING WANG</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences</s1><s2>Harbin</s2><s3>CHN</s3><sZ>1 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ><sZ>10 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>16 aut.</sZ><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>26 aut.</sZ></inist:fA14><country>République populaire de Chine</country><wicri:noRegion>Harbin</wicri:noRegion></affiliation></author><author><name sortKey="Changwen Li" sort="Changwen Li" uniqKey="Changwen Li" last="Changwen Li">CHANGWEN LI</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences</s1><s2>Harbin</s2><s3>CHN</s3><sZ>1 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ><sZ>10 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>16 aut.</sZ><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>26 aut.</sZ></inist:fA14><country>République populaire de Chine</country><wicri:noRegion>Harbin</wicri:noRegion></affiliation></author><author><name sortKey="Shengwang Liu" sort="Shengwang Liu" uniqKey="Shengwang Liu" last="Shengwang Liu">SHENGWANG LIU</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences</s1><s2>Harbin</s2><s3>CHN</s3><sZ>1 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ><sZ>10 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>16 aut.</sZ><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>26 aut.</sZ></inist:fA14><country>République populaire de Chine</country><wicri:noRegion>Harbin</wicri:noRegion></affiliation></author><author><name sortKey="Ming Liao" sort="Ming Liao" uniqKey="Ming Liao" last="Ming Liao">MING LIAO</name><affiliation wicri:level="3"><inist:fA14 i1="03"><s1>College of Veterinary Medicine, South China Agriculture University</s1><s2>Guangzhou</s2><s3>CHN</s3><sZ>3 aut.</sZ><sZ>15 aut.</sZ><sZ>19 aut.</sZ></inist:fA14><country>République populaire de Chine</country><placeName><settlement type="city">Jiangmen</settlement><region type="province">Guangdong</region></placeName></affiliation></author><author><name sortKey="Li Feng" sort="Li Feng" uniqKey="Li Feng" last="Li Feng">LI FENG</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences</s1><s2>Harbin</s2><s3>CHN</s3><sZ>1 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ><sZ>10 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>16 aut.</sZ><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>26 aut.</sZ></inist:fA14><country>République populaire de Chine</country><wicri:noRegion>Harbin</wicri:noRegion></affiliation></author><author><name sortKey="Hua Xiang" sort="Hua Xiang" uniqKey="Hua Xiang" last="Hua Xiang">HUA XIANG</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Military Veterinary Research Institute, Academy of Military Medical Sciences</s1><s2>Changchun</s2><s3>CHN</s3><sZ>2 aut.</sZ><sZ>9 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ></inist:fA14><country>République populaire de Chine</country><placeName><settlement type="city">Changchun</settlement><region type="province">Jilin</region><region type="groupement">Dongbei</region></placeName></affiliation></author><author><name sortKey="Jinfu Sun" sort="Jinfu Sun" uniqKey="Jinfu Sun" last="Jinfu Sun">JINFU SUN</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Military Veterinary Research Institute, Academy of Military Medical Sciences</s1><s2>Changchun</s2><s3>CHN</s3><sZ>2 aut.</sZ><sZ>9 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ></inist:fA14><country>République populaire de Chine</country><placeName><settlement type="city">Changchun</settlement><region type="province">Jilin</region><region type="groupement">Dongbei</region></placeName></affiliation></author><author><name sortKey="Jinding Chen" sort="Jinding Chen" uniqKey="Jinding Chen" last="Jinding Chen">JINDING CHEN</name><affiliation wicri:level="3"><inist:fA14 i1="03"><s1>College of Veterinary Medicine, South China Agriculture University</s1><s2>Guangzhou</s2><s3>CHN</s3><sZ>3 aut.</sZ><sZ>15 aut.</sZ><sZ>19 aut.</sZ></inist:fA14><country>République populaire de Chine</country><placeName><settlement type="city">Jiangmen</settlement><region type="province">Guangdong</region></placeName></affiliation></author><author><name sortKey="Yanwei Sun" sort="Yanwei Sun" uniqKey="Yanwei Sun" last="Yanwei Sun">YANWEI SUN</name><affiliation wicri:level="3"><inist:fA14 i1="05"><s1>Guangdong Provincial Veterinary Station of Epidemic Prevention and Supervision</s1><s2>Guangzhou</s2><s3>CHN</s3><sZ>7 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>République populaire de Chine</country><placeName><settlement type="city">Jiangmen</settlement><region type="province">Guangdong</region></placeName></affiliation></author><author><name sortKey="Shoulin Gu" sort="Shoulin Gu" uniqKey="Shoulin Gu" last="Shoulin Gu">SHOULIN GU</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences</s1><s2>Harbin</s2><s3>CHN</s3><sZ>1 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ><sZ>10 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>16 aut.</sZ><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>26 aut.</sZ></inist:fA14><country>République populaire de Chine</country><wicri:noRegion>Harbin</wicri:noRegion></affiliation></author><author><name sortKey="Nihong Liu" sort="Nihong Liu" uniqKey="Nihong Liu" last="Nihong Liu">NIHONG LIU</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences</s1><s2>Harbin</s2><s3>CHN</s3><sZ>1 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ><sZ>10 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>16 aut.</sZ><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>26 aut.</sZ></inist:fA14><country>République populaire de Chine</country><wicri:noRegion>Harbin</wicri:noRegion></affiliation></author><author><name sortKey="Dexia Fu" sort="Dexia Fu" uniqKey="Dexia Fu" last="Dexia Fu">DEXIA FU</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences</s1><s2>Harbin</s2><s3>CHN</s3><sZ>1 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ><sZ>10 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>16 aut.</sZ><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>26 aut.</sZ></inist:fA14><country>République populaire de Chine</country><wicri:noRegion>Harbin</wicri:noRegion></affiliation></author><author><name sortKey="Eaton, Bryan T" sort="Eaton, Bryan T" uniqKey="Eaton B" first="Bryan T." last="Eaton">Bryan T. Eaton</name><affiliation wicri:level="1"><inist:fA14 i1="06"><s1>Commonwealth Scientific and Industrial Research Organization Livestock Industries, Australian Animal Health Laboratory</s1><s2>Geelong</s2><s3>AUS</s3><sZ>11 aut.</sZ><sZ>24 aut.</sZ><sZ>25 aut.</sZ></inist:fA14><country>Australie</country><wicri:noRegion>Geelong</wicri:noRegion></affiliation></author><author><name sortKey="Wang, Lin Fa" sort="Wang, Lin Fa" uniqKey="Wang L" first="Lin-Fa" last="Wang">Lin-Fa Wang</name><affiliation wicri:level="1"><inist:fA14 i1="06"><s1>Commonwealth Scientific and Industrial Research Organization Livestock Industries, Australian Animal Health Laboratory</s1><s2>Geelong</s2><s3>AUS</s3><sZ>11 aut.</sZ><sZ>24 aut.</sZ><sZ>25 aut.</sZ></inist:fA14><country>Australie</country><wicri:noRegion>Geelong</wicri:noRegion></affiliation></author><author><name sortKey="Xiangang Kong" sort="Xiangang Kong" uniqKey="Xiangang Kong" last="Xiangang Kong">XIANGANG KONG</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences</s1><s2>Harbin</s2><s3>CHN</s3><sZ>1 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ><sZ>10 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>16 aut.</sZ><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>26 aut.</sZ></inist:fA14><country>République populaire de Chine</country><wicri:noRegion>Harbin</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">05-0133641</idno><date when="2005">2005</date><idno type="stanalyst">PASCAL 05-0133641 INIST</idno><idno type="RBID">Pascal:05-0133641</idno><idno type="wicri:Area/PascalFrancis/Corpus">000719</idno><idno type="wicri:Area/PascalFrancis/Curation">000271</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">000688</idno><idno type="wicri:explorRef" wicri:stream="PascalFrancis" 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aut.</sZ><sZ>26 aut.</sZ></inist:fA14><country>République populaire de Chine</country><wicri:noRegion>Harbin</wicri:noRegion></affiliation></author><author><name sortKey="Changchun Tu" sort="Changchun Tu" uniqKey="Changchun Tu" last="Changchun Tu">CHANGCHUN TU</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Military Veterinary Research Institute, Academy of Military Medical Sciences</s1><s2>Changchun</s2><s3>CHN</s3><sZ>2 aut.</sZ><sZ>9 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ></inist:fA14><country>République populaire de Chine</country><placeName><settlement type="city">Changchun</settlement><region type="province">Jilin</region><region type="groupement">Dongbei</region></placeName></affiliation></author><author><name sortKey="Chaoan Xin" sort="Chaoan Xin" uniqKey="Chaoan Xin" last="Chaoan Xin">CHAOAN XIN</name><affiliation wicri:level="3"><inist:fA14 i1="03"><s1>College of Veterinary Medicine, South China Agriculture University</s1><s2>Guangzhou</s2><s3>CHN</s3><sZ>3 aut.</sZ><sZ>15 aut.</sZ><sZ>19 aut.</sZ></inist:fA14><country>République populaire de Chine</country><placeName><settlement type="city">Jiangmen</settlement><region type="province">Guangdong</region></placeName></affiliation></author><author><name sortKey="Hua Xuan" sort="Hua Xuan" uniqKey="Hua Xuan" last="Hua Xuan">HUA XUAN</name><affiliation wicri:level="3"><inist:fA14 i1="04"><s1>Department of Military Veterinary, Changchun University of Agriculture and Animal Sciences</s1><s2>Changchun</s2><s3>CHN</s3><sZ>4 aut.</sZ></inist:fA14><country>République populaire de Chine</country><placeName><settlement type="city">Changchun</settlement><region type="province">Jilin</region><region type="groupement">Dongbei</region></placeName></affiliation></author><author><name sortKey="Qingwen Meng" sort="Qingwen Meng" uniqKey="Qingwen Meng" last="Qingwen Meng">QINGWEN MENG</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences</s1><s2>Harbin</s2><s3>CHN</s3><sZ>1 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ><sZ>10 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>16 aut.</sZ><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>26 aut.</sZ></inist:fA14><country>République populaire de Chine</country><wicri:noRegion>Harbin</wicri:noRegion></affiliation></author><author><name sortKey="Yonggang Liu" sort="Yonggang Liu" uniqKey="Yonggang Liu" last="Yonggang Liu">YONGGANG LIU</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences</s1><s2>Harbin</s2><s3>CHN</s3><sZ>1 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ><sZ>10 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>16 aut.</sZ><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>26 aut.</sZ></inist:fA14><country>République populaire de Chine</country><wicri:noRegion>Harbin</wicri:noRegion></affiliation></author><author><name sortKey="Yedong Yu" sort="Yedong Yu" uniqKey="Yedong Yu" last="Yedong Yu">YEDONG YU</name><affiliation wicri:level="3"><inist:fA14 i1="05"><s1>Guangdong Provincial Veterinary Station of Epidemic Prevention and Supervision</s1><s2>Guangzhou</s2><s3>CHN</s3><sZ>7 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>République populaire de Chine</country><placeName><settlement type="city">Jiangmen</settlement><region type="province">Guangdong</region></placeName></affiliation></author><author><name sortKey="Yuntao Guan" sort="Yuntao Guan" uniqKey="Yuntao Guan" last="Yuntao Guan">YUNTAO GUAN</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences</s1><s2>Harbin</s2><s3>CHN</s3><sZ>1 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ><sZ>10 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>16 aut.</sZ><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>26 aut.</sZ></inist:fA14><country>République populaire de Chine</country><wicri:noRegion>Harbin</wicri:noRegion></affiliation></author><author><name sortKey="Yu Jiang" sort="Yu Jiang" uniqKey="Yu Jiang" last="Yu Jiang">YU JIANG</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Military Veterinary Research Institute, Academy of Military Medical Sciences</s1><s2>Changchun</s2><s3>CHN</s3><sZ>2 aut.</sZ><sZ>9 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ></inist:fA14><country>République populaire de Chine</country><placeName><settlement type="city">Changchun</settlement><region type="province">Jilin</region><region type="groupement">Dongbei</region></placeName></affiliation></author><author><name sortKey="Xunnan Yin" sort="Xunnan Yin" uniqKey="Xunnan Yin" last="Xunnan Yin">XUNNAN YIN</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences</s1><s2>Harbin</s2><s3>CHN</s3><sZ>1 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ><sZ>10 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>16 aut.</sZ><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>26 aut.</sZ></inist:fA14><country>République populaire de Chine</country><wicri:noRegion>Harbin</wicri:noRegion></affiliation></author><author><name sortKey="Crameri, Gary" sort="Crameri, Gary" uniqKey="Crameri G" first="Gary" last="Crameri">Gary Crameri</name><affiliation wicri:level="1"><inist:fA14 i1="06"><s1>Commonwealth Scientific and Industrial Research Organization Livestock Industries, Australian Animal Health Laboratory</s1><s2>Geelong</s2><s3>AUS</s3><sZ>11 aut.</sZ><sZ>24 aut.</sZ><sZ>25 aut.</sZ></inist:fA14><country>Australie</country><wicri:noRegion>Geelong</wicri:noRegion></affiliation></author><author><name sortKey="Muping Wang" sort="Muping Wang" uniqKey="Muping Wang" last="Muping Wang">MUPING WANG</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences</s1><s2>Harbin</s2><s3>CHN</s3><sZ>1 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ><sZ>10 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>16 aut.</sZ><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>26 aut.</sZ></inist:fA14><country>République populaire de Chine</country><wicri:noRegion>Harbin</wicri:noRegion></affiliation></author><author><name sortKey="Changwen Li" sort="Changwen Li" uniqKey="Changwen Li" last="Changwen Li">CHANGWEN LI</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences</s1><s2>Harbin</s2><s3>CHN</s3><sZ>1 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ><sZ>10 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>16 aut.</sZ><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>26 aut.</sZ></inist:fA14><country>République populaire de Chine</country><wicri:noRegion>Harbin</wicri:noRegion></affiliation></author><author><name sortKey="Shengwang Liu" sort="Shengwang Liu" uniqKey="Shengwang Liu" last="Shengwang Liu">SHENGWANG LIU</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences</s1><s2>Harbin</s2><s3>CHN</s3><sZ>1 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ><sZ>10 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>16 aut.</sZ><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>26 aut.</sZ></inist:fA14><country>République populaire de Chine</country><wicri:noRegion>Harbin</wicri:noRegion></affiliation></author><author><name sortKey="Ming Liao" sort="Ming Liao" uniqKey="Ming Liao" last="Ming Liao">MING LIAO</name><affiliation wicri:level="3"><inist:fA14 i1="03"><s1>College of Veterinary Medicine, South China Agriculture University</s1><s2>Guangzhou</s2><s3>CHN</s3><sZ>3 aut.</sZ><sZ>15 aut.</sZ><sZ>19 aut.</sZ></inist:fA14><country>République populaire de Chine</country><placeName><settlement type="city">Jiangmen</settlement><region type="province">Guangdong</region></placeName></affiliation></author><author><name sortKey="Li Feng" sort="Li Feng" uniqKey="Li Feng" last="Li Feng">LI FENG</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences</s1><s2>Harbin</s2><s3>CHN</s3><sZ>1 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ><sZ>10 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>16 aut.</sZ><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>26 aut.</sZ></inist:fA14><country>République populaire de Chine</country><wicri:noRegion>Harbin</wicri:noRegion></affiliation></author><author><name sortKey="Hua Xiang" sort="Hua Xiang" uniqKey="Hua Xiang" last="Hua Xiang">HUA XIANG</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Military Veterinary Research Institute, Academy of Military Medical Sciences</s1><s2>Changchun</s2><s3>CHN</s3><sZ>2 aut.</sZ><sZ>9 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ></inist:fA14><country>République populaire de Chine</country><placeName><settlement type="city">Changchun</settlement><region type="province">Jilin</region><region type="groupement">Dongbei</region></placeName></affiliation></author><author><name sortKey="Jinfu Sun" sort="Jinfu Sun" uniqKey="Jinfu Sun" last="Jinfu Sun">JINFU SUN</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Military Veterinary Research Institute, Academy of Military Medical Sciences</s1><s2>Changchun</s2><s3>CHN</s3><sZ>2 aut.</sZ><sZ>9 aut.</sZ><sZ>17 aut.</sZ><sZ>18 aut.</sZ></inist:fA14><country>République populaire de Chine</country><placeName><settlement type="city">Changchun</settlement><region type="province">Jilin</region><region type="groupement">Dongbei</region></placeName></affiliation></author><author><name sortKey="Jinding Chen" sort="Jinding Chen" uniqKey="Jinding Chen" last="Jinding Chen">JINDING CHEN</name><affiliation wicri:level="3"><inist:fA14 i1="03"><s1>College of Veterinary Medicine, South China Agriculture University</s1><s2>Guangzhou</s2><s3>CHN</s3><sZ>3 aut.</sZ><sZ>15 aut.</sZ><sZ>19 aut.</sZ></inist:fA14><country>République populaire de Chine</country><placeName><settlement type="city">Jiangmen</settlement><region type="province">Guangdong</region></placeName></affiliation></author><author><name sortKey="Yanwei Sun" sort="Yanwei Sun" uniqKey="Yanwei Sun" last="Yanwei Sun">YANWEI SUN</name><affiliation wicri:level="3"><inist:fA14 i1="05"><s1>Guangdong Provincial Veterinary Station of Epidemic Prevention and Supervision</s1><s2>Guangzhou</s2><s3>CHN</s3><sZ>7 aut.</sZ><sZ>20 aut.</sZ></inist:fA14><country>République populaire de Chine</country><placeName><settlement type="city">Jiangmen</settlement><region type="province">Guangdong</region></placeName></affiliation></author><author><name sortKey="Shoulin Gu" sort="Shoulin Gu" uniqKey="Shoulin Gu" last="Shoulin Gu">SHOULIN GU</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences</s1><s2>Harbin</s2><s3>CHN</s3><sZ>1 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ><sZ>10 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>16 aut.</sZ><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>26 aut.</sZ></inist:fA14><country>République populaire de Chine</country><wicri:noRegion>Harbin</wicri:noRegion></affiliation></author><author><name sortKey="Nihong Liu" sort="Nihong Liu" uniqKey="Nihong Liu" last="Nihong Liu">NIHONG LIU</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences</s1><s2>Harbin</s2><s3>CHN</s3><sZ>1 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ><sZ>10 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>16 aut.</sZ><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>26 aut.</sZ></inist:fA14><country>République populaire de Chine</country><wicri:noRegion>Harbin</wicri:noRegion></affiliation></author><author><name sortKey="Dexia Fu" sort="Dexia Fu" uniqKey="Dexia Fu" last="Dexia Fu">DEXIA FU</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences</s1><s2>Harbin</s2><s3>CHN</s3><sZ>1 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ><sZ>10 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>16 aut.</sZ><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>26 aut.</sZ></inist:fA14><country>République populaire de Chine</country><wicri:noRegion>Harbin</wicri:noRegion></affiliation></author><author><name sortKey="Eaton, Bryan T" sort="Eaton, Bryan T" uniqKey="Eaton B" first="Bryan T." last="Eaton">Bryan T. Eaton</name><affiliation wicri:level="1"><inist:fA14 i1="06"><s1>Commonwealth Scientific and Industrial Research Organization Livestock Industries, Australian Animal Health Laboratory</s1><s2>Geelong</s2><s3>AUS</s3><sZ>11 aut.</sZ><sZ>24 aut.</sZ><sZ>25 aut.</sZ></inist:fA14><country>Australie</country><wicri:noRegion>Geelong</wicri:noRegion></affiliation></author><author><name sortKey="Wang, Lin Fa" sort="Wang, Lin Fa" uniqKey="Wang L" first="Lin-Fa" last="Wang">Lin-Fa Wang</name><affiliation wicri:level="1"><inist:fA14 i1="06"><s1>Commonwealth Scientific and Industrial Research Organization Livestock Industries, Australian Animal Health Laboratory</s1><s2>Geelong</s2><s3>AUS</s3><sZ>11 aut.</sZ><sZ>24 aut.</sZ><sZ>25 aut.</sZ></inist:fA14><country>Australie</country><wicri:noRegion>Geelong</wicri:noRegion></affiliation></author><author><name sortKey="Xiangang Kong" sort="Xiangang Kong" uniqKey="Xiangang Kong" last="Xiangang Kong">XIANGANG KONG</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences</s1><s2>Harbin</s2><s3>CHN</s3><sZ>1 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>8 aut.</sZ><sZ>10 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>16 aut.</sZ><sZ>21 aut.</sZ><sZ>22 aut.</sZ><sZ>23 aut.</sZ><sZ>26 aut.</sZ></inist:fA14><country>République populaire de Chine</country><wicri:noRegion>Harbin</wicri:noRegion></affiliation></author></analytic><series><title level="j" type="main">Journal of virology</title><title level="j" type="abbreviated">J. virol.</title><idno type="ISSN">0022-538X</idno><imprint><date when="2005">2005</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Journal of virology</title><title level="j" type="abbreviated">J. virol.</title><idno type="ISSN">0022-538X</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Coronavirus</term><term>Isolate</term><term>Microbiology</term><term>Severe acute respiratory syndrome</term><term>Virology</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Coronavirus</term><term>Isolat</term><term>Microbiologie</term><term>Virologie</term><term>Syndrome respiratoire aigu sévère</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Severe acute respiratory syndrome (SARS) was caused by a novel virus now known as SARS coronavirus (SARS-CoV). The discovery of SARS-CoV-like viruses in masked palm civets (Paguma larvata) raises the possibility that civets play a role in SARS-CoV transmission. To test the susceptibility of civets to experimental infection by different SARS-CoV isolates, 10 civets were inoculated with two human isolates of SARS-CoV, BJ01 (with a 29-nucleotide deletion) and GZ01 (without the 29-nucleotide deletion). All inoculated animals displayed clinical symptoms, such as fever, lethargy, and loss of aggressiveness, and the infection was confirmed by virus isolation, detection of viral genomic RNA, and serum-neutralizing antibodies. Our data show that civets were equally susceptible to SARS-CoV isolates GZ01 and BJ01.</div></front></TEI><affiliations><list><country><li>Australie</li><li>République populaire de Chine</li></country><region><li>Dongbei</li><li>Guangdong</li><li>Jilin</li></region><settlement><li>Changchun</li><li>Jiangmen</li></settlement></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Donglai Wu" sort="Donglai Wu" uniqKey="Donglai Wu" last="Donglai Wu">DONGLAI WU</name></noRegion><name sortKey="Changchun Tu" sort="Changchun Tu" uniqKey="Changchun Tu" last="Changchun Tu">CHANGCHUN TU</name><name sortKey="Changwen Li" sort="Changwen Li" uniqKey="Changwen Li" last="Changwen Li">CHANGWEN LI</name><name sortKey="Chaoan Xin" sort="Chaoan Xin" uniqKey="Chaoan Xin" last="Chaoan Xin">CHAOAN XIN</name><name sortKey="Dexia Fu" sort="Dexia Fu" uniqKey="Dexia Fu" last="Dexia Fu">DEXIA FU</name><name sortKey="Hua Xiang" sort="Hua Xiang" uniqKey="Hua Xiang" last="Hua Xiang">HUA XIANG</name><name sortKey="Hua Xuan" sort="Hua Xuan" uniqKey="Hua Xuan" last="Hua Xuan">HUA XUAN</name><name sortKey="Jinding Chen" sort="Jinding Chen" uniqKey="Jinding Chen" last="Jinding Chen">JINDING CHEN</name><name sortKey="Jinfu Sun" sort="Jinfu Sun" uniqKey="Jinfu Sun" last="Jinfu Sun">JINFU SUN</name><name sortKey="Li Feng" sort="Li Feng" uniqKey="Li Feng" last="Li Feng">LI FENG</name><name sortKey="Ming Liao" sort="Ming Liao" uniqKey="Ming Liao" last="Ming Liao">MING LIAO</name><name sortKey="Muping Wang" sort="Muping Wang" uniqKey="Muping Wang" last="Muping Wang">MUPING WANG</name><name sortKey="Nihong Liu" sort="Nihong Liu" uniqKey="Nihong Liu" last="Nihong Liu">NIHONG LIU</name><name sortKey="Qingwen Meng" sort="Qingwen Meng" uniqKey="Qingwen Meng" last="Qingwen Meng">QINGWEN MENG</name><name sortKey="Shengwang Liu" sort="Shengwang Liu" uniqKey="Shengwang Liu" last="Shengwang Liu">SHENGWANG LIU</name><name sortKey="Shoulin Gu" sort="Shoulin Gu" uniqKey="Shoulin Gu" last="Shoulin Gu">SHOULIN GU</name><name sortKey="Xiangang Kong" sort="Xiangang Kong" uniqKey="Xiangang Kong" last="Xiangang Kong">XIANGANG KONG</name><name sortKey="Xunnan Yin" sort="Xunnan Yin" uniqKey="Xunnan Yin" last="Xunnan Yin">XUNNAN YIN</name><name sortKey="Yanwei Sun" sort="Yanwei Sun" uniqKey="Yanwei Sun" last="Yanwei Sun">YANWEI SUN</name><name sortKey="Yedong Yu" sort="Yedong Yu" uniqKey="Yedong Yu" last="Yedong Yu">YEDONG YU</name><name sortKey="Yonggang Liu" sort="Yonggang Liu" uniqKey="Yonggang Liu" last="Yonggang Liu">YONGGANG LIU</name><name sortKey="Yu Jiang" sort="Yu Jiang" uniqKey="Yu Jiang" last="Yu Jiang">YU JIANG</name><name sortKey="Yuntao Guan" sort="Yuntao Guan" uniqKey="Yuntao Guan" last="Yuntao Guan">YUNTAO GUAN</name></country><country name="Australie"><noRegion><name sortKey="Crameri, Gary" sort="Crameri, Gary" uniqKey="Crameri G" first="Gary" last="Crameri">Gary Crameri</name></noRegion><name sortKey="Eaton, Bryan T" sort="Eaton, Bryan T" uniqKey="Eaton B" first="Bryan T." last="Eaton">Bryan T. Eaton</name><name sortKey="Wang, Lin Fa" sort="Wang, Lin Fa" uniqKey="Wang L" first="Lin-Fa" last="Wang">Lin-Fa Wang</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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